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Can CAH Navigate IRA Pricing Changes Risk Without Margin Pressure?

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Key Takeaways

  • Cardinal Health expects 2027 IRA changes to create a Pharma revenue headwind similar to fiscal 2026.
  • Management aims to preserve compensation as regulatory changes reshape underlying transaction models.
  • Brand and generic volumes plus higher-margin Specialty operations are expected to aid Pharma profit growth.

Cardinal Health (CAH - Free Report) has entered fiscal 2027 with regulatory changes remaining a key headwind for its Pharma business, particularly the impact of Inflation Reduction Act (IRA) pricing changes. In the fourth quarter, IRA-related WACC changes represented an approximately 500-basis-point headwind to Pharma revenues, roughly offsetting a similarly sized GLP-1 tailwind.

For fiscal 2027, CAH expects the annualization of 2026 IRA price changes and implementation of 2027 changes to create a comparable revenue headwind, but management expects no adverse profit impact.

The key to CAH’s approach is maintaining compensation for the services it provides rather than absorbing the economics of regulatory changes. Management said the company works closely with customers and manufacturers to understand regulatory changes and their logistical implications, while maintaining that its compensation should not change as long as its role remains unchanged. The company also noted that the underlying transaction models may evolve, requiring CAH to adapt upstream or downstream.

Distribution agreements provide another layer of protection. CAH highlighted the durability of its core distribution business and its ability to remain compensated for the value it provides during regulatory transitions. Its long-term customer relationships, including a major GMPD renewal and an extended Kroger relationship, provide additional commercial stability.

Manufacturer pricing adjustments could still reshape revenue flows, particularly as IRA changes may involve rebates or WACC reductions. However, CAH says a large portion of the impact flows through revenues without materially affecting profitability. Management therefore expects policy-driven revenue pressure to coexist with continued Pharma profit growth, supported by brand and generic volumes and higher-margin Specialty operations.

Peer Updates

IRA pricing changes are creating a meaningful revenue headwind but a relatively limited direct EBITDA impact for BrightSpring Health Services (BTSG - Free Report) . Management expects the IRA to reduce Home and Community Pharmacy revenues by approximately $200 million in 2026, or about $50 million per quarter, while estimating the corresponding EBITDA impact at only $15 million for the full year.

In Specialty and Infusion, the company expects roughly $175 million of revenue pressure but essentially no EBITDA impact. Management attributed this resilience to operational initiatives, including technology, automation and AI investments, which are improving efficiency and helping offset regulatory pressures.

CVS Health's (CVS - Free Report) pharmacy economics is already getting affected by the regulatory drug-price reductions, although the company did not separately quantify the IRA's specific margin impact. Pharmacy & Consumer Wellness revenues were pressured by regulatory-related price reductions on certain drugs, generic introductions and reimbursement pressure, while adjusted operating income still increased more than 10% year over year.

In Caremark, CVS is transitioning toward net-cost pricing models amid regulatory developments, with management emphasizing that the transition is intended to preserve the value delivered by the PBM. The company also expects to maintain margins at historical industry levels over time, supported by specialty pharmacy, generic penetration, purchasing economics and operational improvements.

CAH’s Price Performance, Valuation and Estimates

Shares of CAH have gained 13.2% so far this year compared with the industry’s  5% growth.

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From a valuation standpoint, Cardinal Health trades at a forward price-to-earnings of 18.12X, above the industry average. However, it is trading lower than its five-year high of 22.19X. CAH carries a Value Score of A.

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The Zacks Consensus Estimate for Cardinal Health’s fiscal 2027 earnings implies an 11.5% rise from the year-ago reported number.

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The company currently carries a Zacks Rank #3 (Hold). You can see the complete list of today’s Zacks #1 Rank (Strong Buy) stocks here.

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